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The regulation requires manufacturers to carry out tests to assess the risk of a new substance to humans, animals and the environment

These findings highlight the potential of combination strategies to maximize metabolic benefits, warranting further investigation in clinical studies

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Nat Rev Neurosci 9:182194 Boehme M, Van de Wouw M, Van Sandhu K et al (2018) Targeting the gut microbiome to reverse microglia activation and stress-induced immune priming in ageing